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National One Health Mission

Indian Council of Medical Research | Government of India

One Health is an integrating idea that brings different sectors together to solve the health, productivity, and conservation challenges and has major implications for India. India with its diverse wildlife, one of the largest livestock populations and high density of human population, and diversity of flora, creates opportunities for harmonious coexistence or conflicts such as heightened risks for inter-compartmental spread of diseases. The COVID-19 pandemic, recent outbreak of Lumpy Skin Disease in cattle, and the constant threat of Avian Influenza show that it is not just about addressing diseases from human health point of view (zoonosis) but there is also a need to address the livestock, wildlife and environmental aspects, including plants. This also opens opportunity for leveraging the complementarities and strengths that is inherent in each sector and devises integrated, robust and agile response systems. The complexity and interconnectedness of the challenges threatening humans, animals, and environment including plants, where they coexist, therefore requires a holistic and integrated ‘One Health’ based approach to achieve the goal of ‘Health and Wellness for All’.

Office of the Prinicipal Scientific Adviser : National One Health Mission (PSA website)

 

 

 

‘To build an integrated disease control and pandemic preparedness system in India by bringing human, animal and environmental sectors together for better health outcomes, improved productivity and conservation of biodiversity.’

The key goals of the One Health Mission will be towards enabling and achieving the stated vision, making the mission responsive to the needs of the human-animal-environment interface, establishing a broad based inclusive collaboration for achieving the nation’s health goals, and reducing the existing disease burden. To achieve these goals, the One Health Mission also aspires to implement the following strategies, which are ongoing and will be strengthened under the mission along with several other new activities:

  1. Capacity building, collaboration, communication and storage of potential high- risk pathogens
  2. Creation of a national network of existing and upcoming high-risk pathogens laboratories (BSL-3/4) labs across departments and keeping them functional through continuous R&D and use during outbreak response
  3. Developing and assessing the feasibility of various tools (AI tools, NGS, diagnostic algorithms for detection/discovery of emerging novel pathogens in humans, animals and environment and establish metagenomic pipelines for novel pathogen discovery.
  4. Develop protocols, tools and framework for integrated disease surveillance at the animal-human-environment interface for emerging diseases.
  5. Plug and play vaccine platforms, diagnostics, capacity for development of high quality therapeutic monoclonal.
  6. Develop analytic capability to derive better insights from the data and information of human, livestock and wildlife sectors

The Indian Council of Medical Research is in the process of establishing “Infectious Disease Research and Diagnostic Laboratories (IRDLs)” in State/Central Govt run institutes and medical colleges with functioning Virus Research and Diagnostic Laboratories (VRDLs), with the view of strengthening the verticals of diagnostic Bacteriology, Mycology and Parasitology. These institutes shall serve as Regional Referral level labs for diagnosis and research on infectious diseases, and shall be supported by ICMR with funding for equipment, infrastructure, manpower and consumables. These institutes shall have the following mandate:

  1. Quality assured advanced diagnostic testing of infectious diseases, including outbreak investigations
  2. Syndromic surveillance of infectious diseases
  3. Role as biorepositories/biobanks with well characterized relevant microbe strains and clinical samples
  4. Role as certified PT panel providers for infectious disease testing
  5. Role as accredited in-vitro diagnostics evaluation centers

ICMR has shortlisted eight (08) VRDLs for the establishment of IRDLs in the pilot phase through rigorous internal and external review, including on-site assessment. These sites (enlisted in Table 1) are in various stages of IRDL establishment.

RegionIRDL SiteFunding status
North IndiaKing George’s Medical University, Lucknow, Uttar PradeshFunded in August 2024
North IndiaAll India Institute of Medical Sciences, DelhiFunded in December 2024
Central IndiaAll India Institute of Medical Sciences, Raipur, ChhattisgarhFunded in August 2024
Central IndiaAll India Institute of Medical Sciences, Bhopal, Madhya PradeshFunded in December 2024
South IndiaBangalore Medical College and Research Institute, Bengaluru, KarnatakaFunded in August 2024
Eastern IndiaAll India Institute of Medical Sciences, Bhubaneswar, OdishaFunded in December 2024
Western IndiaAll India Institute of Medical Sciences,Jodhpur, RajasthanFunded in April 2025
North-East IndiaGauhati Medical College, Guwahati, AssamFunded in April 2025

IRDLs are expected to significantly strengthen the diagnostic and research capacity of the country.

IRDL_Sites
 

 

  

 
Human |Animal
Human | Animal | Environment
  
IRDL